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Search Results for " Peroxisome proliferator-activated receptors "

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天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T39516	Bocidelpar		PPAR
	Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.		PPAR
T10900	CUDA		PPAR , Epoxide Hydrolase
	CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR...		PPAR , Epoxide Hydrolase
T1264	Ciprofibrate	Win35833	PPAR
	Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.		PPAR
T15945	MA-0204		PPAR
	MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively). It is a potential treatmen...		PPAR
T6689	T0070907		PPAR
	T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.		PPAR
T8374	LJ570		PPAR
	LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)		PPAR
T5532	BMS-687453		PPAR
	BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.		PPAR
TQ0156	GW1929		PPAR
	GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).		PPAR
T1941	GSK3787		PPAR
	GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.		PPAR
T7159	L-165041		PPAR
	L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)		PPAR
T2674	GSK0660		PPAR
	GSK0660 is an antagonist and inverse agonist of PPARβ/δ.		PPAR
T7395	Lanifibranor	IVA337	PPAR
	Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα, PPARβ, and PPARγ, respectively, for transactivation activ...		PPAR
T24827	SR 16832	SR-16832,SR16832	PPAR
	SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907.		PPAR
T4408	Elafibranor	GFT505	PPAR
	Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively.		PPAR
T8486	GW6471	GW 6471	PPAR
	GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.		PPAR
T3954	Adelmidrol		NF-κB , COX , PPAR
	Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.		NF-κB , COX , PPAR
T9808	Tetradecylthioacetic acid		PPAR
	Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti...		PPAR
T0061	Clofibric acid	Chlorofibrinic acid	PPAR , Drug Metabolite
	Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.		PPAR , Drug Metabolite
T2413	FH535		Wnt/beta-catenin , PPAR
	FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.		Wnt/beta-catenin , PPAR
T21764	MCC-555	Isaglitazone,Netoglitazone	PPAR
	MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.		PPAR
T0841	Bezafibrate	BM15075	PPAR
	Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW-DENSITY LIPOPROTEINS and increases HIGH-DENSITY LIPOPROTEINS.		PPAR
T9766	GW590735		PPAR
	GW590735 is an effective and selective PPARα agonist with an EC50 of 4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW590735 can be used in dyslipidemia studies.		PPAR
T21955	GQ-16		PPAR
	GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.		PPAR
T1149	Fenofibrate	Procetofen,Lipanthyl,Lipantil	P450 , PPAR , Autophagy
	Fenofibrate (Lipanthyl) is a peroxisome proliferator receptor alpha agonist. Fenofibrate is a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.		P450 , PPAR , Autophagy
T8780	AMG131	INT-131,AMG-131,CHS 131	PPAR
	AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende...		PPAR
T23389	SR1664	SR 1664	PPAR
	SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR...		PPAR
T22708	Darglitazone	CP-86325	PPAR
	Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.		PPAR
T1298	Clofibrate	Clofibrato,Clofibratum,Ethyl clofibrate	PPAR
	Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.		PPAR
T4628	Seladelpar	MBX 8025	PPAR
	Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.		PPAR
T15821	LY518674	LY-674	PPAR
	LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis. LY518674 is an effective and selective PPARα agonist (EC50: 42 nM for human PPARα).		PPAR
T2269	Pirinixic Acid	Wy-14643,NSC 310038	PPAR
	Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, carcinogenic Pirinixic acid is a peroxisome proliferator that activates specific peroxisome proliferator-activated recepto...		PPAR
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
T9756	AZD-9574		PARP
	AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.		PARP
T1402	Fenofibric acid	Trilipix,FNF acid,NSC 281318	MMP , COX , PPAR
	Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.		MMP , COX , PPAR
T13289	EHP-101	VCE-004.8	Cannabinoid Receptor , HIF/HIF Prolyl-Hydroxylase , PPAR
	EHP-101 (VCE-004.8) is a specific dual agonist of PPARγ and CB2 receptor with potent anti-inflammatory activity. EHP-101 attenuates adipogenesis and prevents diet-induced obesity.		Cannabinoid Receptor , HIF/HIF Prolyl-Hydroxylase , PPAR
T1415	Gemfibrozil	CI-719,Jezil,Decrelip,Lopid	P450 , Adrenergic Receptor , PPAR
	Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfi...		P450 , Adrenergic Receptor , PPAR
T7821	DG172 dihydrochloride	DG172 (dihydrochloride),DG-172 dihydrochloride	PPAR
	DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).		PPAR
T8638	NPC 15199	FMOC-L-Leucine	Others
	NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.		Others
T16074	Mifobate	SR-202	PPAR
	Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].		PPAR
T0214	Pioglitazone	U 72107	Ferroptosis , PPAR
	Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury.		Ferroptosis , PPAR
T15581	Inolitazone	RS5444,Efatutazone,CS-7017	PPAR
	Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.		PPAR
T3941	Choline Fenofibrate	Trilipix,ABT-335	P450 , COX , PPAR
	Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.		P450 , COX , PPAR
T3170	Troglitazone	CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay	Apoptosis , Ferroptosis , PPAR , Autophagy
	Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.		Apoptosis , Ferroptosis , PPAR , Autophagy
T8505	SC-236	Sc 236	Apoptosis , COX , PPAR
	SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).		Apoptosis , COX , PPAR
T1622	Rosiglitazone maleate	BRL 49653C,BRL 49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone maleate (BRL 49653) is the maleate salt of rosiglitazone, an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T0509	Cloxiquine	5-Chloro-8-quinolinol,Dermofungin,Dermofongin	Antibacterial , Antibiotic , PPAR , Parasite , Antifungal
	Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.		Antibacterial , Antibiotic , PPAR , Parasite , Antifungal
T2260	GW9662	TIMTEC-BB SBB006523,GW 9662	PPAR
	GW9662 (TIMTEC-BB SBB006523) is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.		PPAR
T15453	GW7647		PPAR
	GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).		PPAR
T6893	MK-886	MK886,L 663536	Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
	MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.		Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
TQ0120	CDDO-Im	RTA-403,CDDO-Imidazolide,TP-235	Others , Ferroptosis , Nrf2 , PPAR
	CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).		Others , Ferroptosis , Nrf2 , PPAR

Compounds

Target: PPAR, Epoxide Hydrolase

Synonym: SR-16832,SR16832

Target: NF-κB, COX, PPAR

Tetradecylthioacetic acid

Synonym: Chlorofibrinic acid

Target: PPAR, Drug Metabolite

FH535

T2413

Synonym:

Target: Wnt/beta-catenin, PPAR

MCC-555

T21764

Synonym: Isaglitazone,Netoglitazone

Synonym: Procetofen,Lipanthyl,Lipantil

Target: P450, PPAR, Autophagy

AMG131

T8780

Synonym: INT-131,AMG-131,CHS 131

Synonym: Clofibrato,Clofibratum,Ethyl clofibrate

Synonym: Wy-14643,NSC 310038

Target: PPAR

EPI-001

T6829

Synonym: EPI001,EPI 001

Target: Apoptosis, Androgen Receptor, PPAR

Synonym: Trilipix,FNF acid,NSC 281318

Target: MMP, COX, PPAR

EHP-101

T13289

Synonym: VCE-004.8

Target: Cannabinoid Receptor, HIF/HIF Prolyl-Hydroxylase, PPAR

Gemfibrozil

T1415

Synonym: CI-719,Jezil,Decrelip,Lopid

Target: P450, Adrenergic Receptor, PPAR

DG172 dihydrochloride

T7821

Synonym: DG172 (dihydrochloride),DG-172 dihydrochloride

Target: PPAR

NPC 15199

T8638

Synonym: FMOC-L-Leucine

Target: Ferroptosis, PPAR

Inolitazone

T15581

Synonym: RS5444,Efatutazone,CS-7017

Target: PPAR

Choline Fenofibrate

T3941

Synonym: Trilipix,ABT-335

Target: P450, COX, PPAR

Troglitazone

T3170

Synonym: CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay

Target: Apoptosis, Ferroptosis, PPAR, Autophagy

SC-236

T8505

Synonym: Sc 236

Target: Apoptosis, COX, PPAR

Rosiglitazone maleate

T1622

Synonym: BRL 49653C,BRL 49653

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Cloxiquine

T0509

Synonym: 5-Chloro-8-quinolinol,Dermofungin,Dermofongin

Target: Antibacterial, Antibiotic, PPAR, Parasite, Antifungal

GW9662

T2260

Synonym: TIMTEC-BB SBB006523,GW 9662

Synonym: MK886,L 663536

Target: Apoptosis, Leukotriene Receptor, COX, PPAR, FLAP

CDDO-Im

TQ0120

Synonym: RTA-403,CDDO-Imidazolide,TP-235

Target: Others, Ferroptosis, Nrf2, PPAR

カタログ番号	製品名	別名	ターゲット
TN1693	Glabrone		Influenza Virus , PPAR
	Glabrone shows antiviral activity against influenza virus.		Influenza Virus , PPAR
T3867	Alpinetin	(-)-alpinetin	BCL , PPAR
	Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he...		BCL , PPAR
T4S2128	Bilobetin		PKA , PPAR
	Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.		PKA , PPAR
TN7060	Methyl oleanonate		PPAR
	3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.		PPAR
T1238	Daidzein	Isoflavone	Endogenous Metabolite , PPAR
	Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties.		Endogenous Metabolite , PPAR
T2879	Fisetin		TNF , Sirtuin , PPAR
	Fisetin is a natural flavonol extracted from Rhus succedanea L that is structurally and functionally related to kaempferol, can modulate sirtuins,with antioxidant, anticancer, neuroprotection effects.		TNF , Sirtuin , PPAR
T2985	Gypenoside XLIX		PPAR
	Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition		PPAR
T2855	Icariin	Ieariline	PDE , PPAR , Autophagy
	Icariin (Ieariline) is a flavonol glycoside, inhibiting PDE5 and PDE4 activities. Icariin also is a PPARα activator.		PDE , PPAR , Autophagy
TN1018	Angeloylgomisin H		PPAR
	Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.		PPAR
T3362	Eupatilin	NSC 122413	PPAR , Autophagy
	Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.		PPAR , Autophagy
TN1990	Norathyriol		Akt , DNA/RNA Synthesis , AMPK , PPAR
	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.		Akt , DNA/RNA Synthesis , AMPK , PPAR
T4S1545	Licarin B	(-)-Licarin B,Licarine B	transporter , Antibacterial , PPAR
	1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.		transporter , Antibacterial , PPAR
T5S0788	Oroxin A	Baicalein 7-O-glucoside	PPAR
	Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.		PPAR
T3000	Magnolol	NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T1051	Retinoic acid	Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin	Retinoid Receptor , Endogenous Metabolite , PPAR , Autophagy
	Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferat...
T6917	Oleuropein		Apoptosis , Aromatase , ROS , PPAR
	Oleuropein is an antioxidant polyphenol isolated from olive leaf.		Apoptosis , Aromatase , ROS , PPAR
T5S1550	Cinnamyl alcohol	Cinnamic Alcohol,Styryl Carbinol	PPAR
	Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.		PPAR
T5701	OPHIOPOGONIN D		RAAS , Calcium Channel , NF-κB , PPAR
	Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.		RAAS , Calcium Channel , NF-κB , PPAR
T19500	Palmitelaidic Acid	trans-Palmitoleic acid,9-trans-Hexadecenoic acid	Glucokinase , AMPK , PPAR
	Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.		Glucokinase , AMPK , PPAR
T12296	Oleoylethanolamide	N-Oleoylethanolamide,Oleamide MEA,Oleic acid monoethanolamide	Endogenous Metabolite , PPAR
	Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.		Endogenous Metabolite , PPAR
T0646	5-Aminosalicylic Acid	Mesalazine,5-ASA,Mesalamine	NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR
	5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
T3403	Glabridin	Q-100692,KB-289522,LS-176045	Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR
	Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on...
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
TN3500	Beta-Amyrone	β-Amyron	COX , AChR , PPAR , Antifection
	beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a...		COX , AChR , PPAR , Antifection
T4S1173	Agrimol B		Sirtuin , PPAR
	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.		Sirtuin , PPAR
T2S0633	Raspberry ketone	Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone	PPAR
	1. Raspberry ketone (p-Hydroxybenzyl acetone) is cytotoxic to melanocytes through the binding of RK-derived quinones to thiol proteins and the pro-oxidant activity of the RK-oligomer, the exposure of human skin to RK can...		PPAR
TN1525	Convallatoxin		NF-κB , P-gp , PPAR
	Convallatoxin is a natural product		NF-κB , P-gp , PPAR
T3138	Astaxanthin	β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin	Reactive Oxygen Species , PPAR
	Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aqu...		Reactive Oxygen Species , PPAR
T14046	Anandamide	(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide	Cannabinoid Receptor , Endogenous Metabolite
	Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...		Cannabinoid Receptor , Endogenous Metabolite
T2932	Ginsenoside Rh1	Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.

天然物製品

Glabrone

TN1693

Synonym:

Target: Influenza Virus, PPAR

Alpinetin

T3867

Synonym: (-)-alpinetin

Target: Endogenous Metabolite, PPAR

Fisetin

T2879

Synonym:

Target: TNF, Sirtuin, PPAR

Target: PDE, PPAR, Autophagy

Target: PPAR, Autophagy

Norathyriol

TN1990

Synonym:

Target: Akt, DNA/RNA Synthesis, AMPK, PPAR

Licarin B

T4S1545

Synonym: (-)-Licarin B,Licarine B

Target: transporter, Antibacterial, PPAR

Oroxin A

T5S0788

Synonym: Baicalein 7-O-glucoside

Target: PPAR

Magnolol

T3000

Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

Retinoic acid

T1051

Synonym: Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin

Target: Retinoid Receptor, Endogenous Metabolite, PPAR, Autophagy

Oleuropein

T6917

Synonym:

Target: Apoptosis, Aromatase, ROS, PPAR

Cinnamyl alcohol

T5S1550

Synonym: Cinnamic Alcohol,Styryl Carbinol

Target: RAAS, Calcium Channel, NF-κB, PPAR

Palmitelaidic Acid

T19500

Synonym: trans-Palmitoleic acid,9-trans-Hexadecenoic acid

Target: Glucokinase, AMPK, PPAR

Oleoylethanolamide

T12296

Synonym: N-Oleoylethanolamide,Oleamide MEA,Oleic acid monoethanolamide

Target: Endogenous Metabolite, PPAR

5-Aminosalicylic Acid

T0646

Synonym: Mesalazine,5-ASA,Mesalamine

Target: NF-κB, Lipoxygenase, COX, Glutathione Peroxidase, Endogenous Metabolite, PAK, PPAR

Glabridin

T3403

Synonym: Q-100692,KB-289522,LS-176045

Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR

Target: COX, AChR, PPAR, Antifection

Agrimol B

T4S1173

Synonym:

Target: Sirtuin, PPAR

Raspberry ketone

T2S0633

Synonym: Oxyphenalon,Rasketone,Aloenin,4-(4-Hydroxyphenyl)-2-butanone,p-Hydroxybenzyl acetone,Frambinone

Target: NF-κB, P-gp, PPAR

Astaxanthin

T3138

Synonym: β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin

Target: Reactive Oxygen Species, PPAR

Anandamide

T14046

Synonym: (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Target: Cannabinoid Receptor, Endogenous Metabolite

Ginsenoside Rh1

T2932

Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01213	ASXL1 Protein, Human, Recombinant (GST)	Human	E. coli
	Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma...
TMPY-02239	FABP3 Protein, Human, Recombinant	Human	E. coli
	Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular s...
TMPY-00605	FABP3 Protein, Mouse, Recombinant	Mouse	E. coli
	Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular s...
TMPY-00266	PEDF Protein, Rat, Recombinant (His)	Rat	HEK293
	Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco...
TMPY-01112	PEDF Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco...
TMPY-01328	PEDF Protein, Human, Recombinant (His)	Human	HEK293
	Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco...